Avodart vs Proscar
Avodart (dutasteride) and Proscar (finasteride) are prescription medications used to treat benign prostatic hyperplasia (BPH). Both reduce DHT levels, but Avodart blocks more enzyme types, which may lead to stronger suppression.
Quick Comparison
| Feature | Avodart (Dutasteride) | Proscar (Finasteride) |
|---|---|---|
| How it Works | Blocks type I & II 5α-reductase enzymes | Blocks type II 5α-reductase enzyme |
| DHT Reduction | ~90%+ | ~60–70% |
| Form | Oral capsule | Oral tablet |
| Best For | Moderate to severe BPH | Mild to moderate BPH |
| Time to Results | 3–6 months | 3–6 months |
| Main Side Effects | Sexual dysfunction, reduced libido | Sexual side effects (less frequent) |
| Half-Life | Long (~5 weeks) | Short (~6–8 hours) |
When Avodart May Be Better
Avodart may be more effective for patients with larger prostate size or more severe symptoms due to stronger DHT suppression.
- More potent DHT reduction
- Targets both enzyme types
- May shrink prostate more significantly
- Long-lasting effect in the body
When Proscar May Be Better
Proscar may be preferred for those who want a well-established treatment with a shorter half-life and potentially fewer persistent side effects.
- Long track record of use
- Shorter duration in body
- Often first-line therapy
- Lower overall DHT suppression
Can You Use Them Together?
No. Avodart and Proscar should not be used together because they belong to the same drug class (5-alpha reductase inhibitors) and work via similar mechanisms.
Instead, they are sometimes combined with alpha-blockers (like tamsulosin) for improved symptom relief in BPH.
Compare BPH Treatment Options
Explore consultations, medications, and online providers for prostate health.
FAQ
Is Avodart stronger than Proscar?
Yes, Avodart typically suppresses more DHT because it blocks two enzyme types, while Proscar blocks only one.
Which is safer?
Both medications have similar safety profiles, but Proscar has a longer history of clinical use.
Can they treat hair loss?
Finasteride (Proscar/Propecia) is commonly used for hair loss. Dutasteride is sometimes used off-label.
Do results reverse after stopping?
Yes. Symptoms of BPH may return after discontinuation of treatment.
Informational content only. Not medical advice.